Detalhe da pesquisa
1.
Signaling and Function of Interleukin-2 in T Lymphocytes.
Annu Rev Immunol
; 36: 411-433, 2018 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29677473
2.
Facile discovery of surrogate cytokine agonists.
Cell
; 185(8): 1414-1430.e19, 2022 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35325595
3.
A local regulatory T cell feedback circuit maintains immune homeostasis by pruning self-activated T cells.
Cell
; 184(15): 3981-3997.e22, 2021 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34157301
4.
Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop.
Cell
; 184(15): 3998-4015.e19, 2021 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34157302
5.
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8+ T cells.
Nat Immunol
; 24(5): 869-883, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37081150
6.
How autoreactive thymocytes differentiate into regulatory versus effector CD4+ T cells after avoiding clonal deletion.
Nat Immunol
; 24(4): 637-651, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36959291
7.
Dynamic transcriptional activity and chromatin remodeling of regulatory T cells after varied duration of interleukin-2 receptor signaling.
Nat Immunol
; 23(5): 802-813, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35449416
8.
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation.
Nat Immunol
; 23(6): 878-891, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35618831
9.
Delayed-interval BNT162b2 mRNA COVID-19 vaccination enhances humoral immunity and induces robust T cell responses.
Nat Immunol
; 23(3): 380-385, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35115679
10.
IL-2 regulates tumor-reactive CD8+ T cell exhaustion by activating the aryl hydrocarbon receptor.
Nat Immunol
; 22(3): 358-369, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33432230
11.
Robust SARS-CoV-2-specific T cell immunity is maintained at 6 months following primary infection.
Nat Immunol
; 22(5): 620-626, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33674800
12.
Interleukin-2 signaling in the regulation of T cell biology in autoimmunity and cancer.
Immunity
; 57(3): 414-428, 2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38479359
13.
Something old, something new: The marriage of PD-1 and IL-2.
Immunity
; 56(1): 8-10, 2023 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36630920
14.
Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure.
Immunity
; 56(12): 2699-2718.e11, 2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38091951
15.
Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages.
Immunity
; 56(1): 162-179.e6, 2023 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36630914
16.
Transcription factor Foxp1 regulates Foxp3 chromatin binding and coordinates regulatory T cell function.
Nat Immunol
; 20(2): 232-242, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30643266
17.
c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells.
Nat Immunol
; 19(5): 497-507, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29662170
18.
Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming.
Immunity
; 54(9): 2089-2100.e8, 2021 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34469774
19.
Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke.
Immunity
; 54(7): 1527-1542.e8, 2021 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34015256
20.
A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance.
Immunity
; 54(5): 931-946.e11, 2021 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33838102